He was owned by Gigginstown House Stud and had been quoted at bookmaker odds of 50-1 for the Grand National at Aintree on 14 April.
A Genie In Abottle beat main National hope Tiger Roll when successful at Wexford in October.
The horse was sent off 4-1 favorite for the four-mile National Hunt Chase at last year's Cheltenham Festival, he finished a very respective fifth in the contest.
Meade informed The Guardian newspaper this morning: “We'd been a bit worried about him however the vets could not discover what was wrong with him. “It was clearly very critical as a result of we discovered him on the ground of his box.” Gigginstown spokesman Eddie O'Leary mentioned: “We've no concept what occurred. He was OK in the morning and dead in his box at Friday lunchtime.”
Gigginstown hopes to have five runners contending the Grand National Aintree race – Tiger Roll, Alpha Des Obeaux, Thunder And Roses, Valseur Lido and Road To Riches.
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